BDBM50126016 2-(3-chloro-4-(3-(3-ethyl-7-propylbenzo[d]isoxazol-6-yloxy)propylthio)phenyl)acetic acid::CHEMBL279053::{3-Chloro-4-[3-(3-ethyl-7-propyl-benzo[d]isoxazol-6-yloxy)-propylsulfanyl]-phenyl}-acetic acid

SMILES CCCc1c(OCCCSc2ccc(CC(O)=O)cc2Cl)ccc2c(CC)noc12

InChI Key InChIKey=LBEYMGDIPDOUKK-UHFFFAOYSA-N

Data  7 IC50  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50126016   

TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50126016(2-(3-chloro-4-(3-(3-ethyl-7-propylbenzo[d]isoxazol...)
Affinity DataEC50:  11nMAssay Description:Transcriptional activation by human PPAR deltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50126016(2-(3-chloro-4-(3-(3-ethyl-7-propylbenzo[d]isoxazol...)
Affinity DataIC50:  110nMAssay Description:In vitro binding affinity for human PPAR gamma in SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50126016(2-(3-chloro-4-(3-(3-ethyl-7-propylbenzo[d]isoxazol...)
Affinity DataEC50:  247nMAssay Description:Transcriptional activation by human PPAR alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50126016(2-(3-chloro-4-(3-(3-ethyl-7-propylbenzo[d]isoxazol...)
Affinity DataIC50:  570nMAssay Description:In vitro binding affinity for human PPAR gamma in SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50126016(2-(3-chloro-4-(3-(3-ethyl-7-propylbenzo[d]isoxazol...)
Affinity DataIC50:  4nMAssay Description:In vitro binding affinity for human PPAR alpha in SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50126016(2-(3-chloro-4-(3-(3-ethyl-7-propylbenzo[d]isoxazol...)
Affinity DataEC50:  19nMAssay Description:In vitro binding affinity for human PPAR gamma in SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50126016(2-(3-chloro-4-(3-(3-ethyl-7-propylbenzo[d]isoxazol...)
Affinity DataIC50:  110nMAssay Description:Agonist activity at PPARgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50126016(2-(3-chloro-4-(3-(3-ethyl-7-propylbenzo[d]isoxazol...)
Affinity DataEC50:  100nMAssay Description:Agonist activity at human PPARgamma ligand binding domain expressed in human 293T cells cotransfected with Gal4-DBD by luciferase transactivation ass...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50126016(2-(3-chloro-4-(3-(3-ethyl-7-propylbenzo[d]isoxazol...)
Affinity DataEC50:  12nMAssay Description:Agonist activity at human PPARdelta ligand binding domain expressed in human 293T cells cotransfected with Gal4-DBD by luciferase transactivation ass...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50126016(2-(3-chloro-4-(3-(3-ethyl-7-propylbenzo[d]isoxazol...)
Affinity DataIC50:  110nMAssay Description:Displacement of radio-labeled full agonist from PPARgamma receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50126016(2-(3-chloro-4-(3-(3-ethyl-7-propylbenzo[d]isoxazol...)
Affinity DataIC50:  570nMAssay Description:Agonist activity at PPARalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50126016(2-(3-chloro-4-(3-(3-ethyl-7-propylbenzo[d]isoxazol...)
Affinity DataIC50:  4nMAssay Description:Agonist activity at PPARdeltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50126016(2-(3-chloro-4-(3-(3-ethyl-7-propylbenzo[d]isoxazol...)
Affinity DataEC50:  1.30E+3nMAssay Description:Agonist activity at human PPARalpha ligand binding domain expressed in human 293T cells cotransfected with Gal4-DBD by luciferase transactivation ass...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed