BDBM50129817 CHEMBL3628685

SMILES COc1ccc(CNC(=O)c2ccc(OC(F)F)c(OC3CCCC3)c2)cc1

InChI Key InChIKey=DBNDIIUELFNMBG-UHFFFAOYSA-N

Data  13 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50129817   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50129817(CHEMBL3628685)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of core catalytic domains of human PDE4 using AM-Cyclic-3',5'-AMP after 60 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50129817(CHEMBL3628685)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human PDE3B using AM-Cyclic-3',5'-AMP after 60 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50129817(CHEMBL3628685)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human PDE5A using AM-Cyclic-3',5'-AMP after 60 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50129817(CHEMBL3628685)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human PDE6C using AM-Cyclic-3',5'-AMP after 60 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50129817(CHEMBL3628685)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human PDE7A using AM-Cyclic-3',5'-AMP after 60 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50129817(CHEMBL3628685)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human PDE8A1 using AM-Cyclic-3',5'-AMP after 60 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50129817(CHEMBL3628685)
Affinity DataIC50:  976nMAssay Description:Inhibition of human full-length PDE4B1 using AM-Cyclic-3',5'-AMP after 60 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50129817(CHEMBL3628685)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human PDE10A2 using AM-Cyclic-3',5'-AMP after 60 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50129817(CHEMBL3628685)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human PDE11A using AM-Cyclic-3',5'-AMP after 60 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50129817(CHEMBL3628685)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human PDE2A using AM-Cyclic-3',5'-AMP after 60 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50129817(CHEMBL3628685)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human PDE1A using AM-Cyclic-3',5'-AMP after 60 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50129817(CHEMBL3628685)
Affinity DataIC50:  94nMAssay Description:Inhibition of human full-length PDE4D7 using AM-Cyclic-3',5'-AMP after 60 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50129817(CHEMBL3628685)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human PDE9A2 using AM-Cyclic-3',5'-AMP after 60 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed