BDBM50130095 6-Methyl-1,2,3,4,5,6-hexahydro-azepino[4,5-b]indole::CHEMBL6557::PNU-22394

SMILES Cn1c2CCNCCc2c2ccccc12

InChI Key InChIKey=ZBXDOQWPGBISAR-UHFFFAOYSA-N

Data  3 KI  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50130095   

Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50130095(6-Methyl-1,2,3,4,5,6-hexahydro-azepino[4,5-b]indol...)
Affinity DataKi:  19nMAssay Description:Binding affinity against 5-hydroxytryptamine 2C receptor using [125I]-DOI radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50130095(6-Methyl-1,2,3,4,5,6-hexahydro-azepino[4,5-b]indol...)
Affinity DataKi:  19nMAssay Description:Binding affinity against 5-hydroxytryptamine 2A receptor using [125I]-DOI radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50130095(6-Methyl-1,2,3,4,5,6-hexahydro-azepino[4,5-b]indol...)
Affinity DataKi:  415nMAssay Description:Binding affinity at alpha-2 adrenergic receptors of rat.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50130095(6-Methyl-1,2,3,4,5,6-hexahydro-azepino[4,5-b]indol...)
Affinity DataEC50:  210nMAssay Description:Agonist activity at human 5HT2A receptor expressed in HEK293 cells assessed as accumulation of IP1 incubated for 1 hr at 37 degC followed by 15 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50130095(6-Methyl-1,2,3,4,5,6-hexahydro-azepino[4,5-b]indol...)
Affinity DataEC50:  120nMAssay Description:Agonist activity at human 5HT2C receptor expressed in HEK293 cells assessed as accumulation of IP1 incubated for 1 hr at 37 degC followed by 15 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50130095(6-Methyl-1,2,3,4,5,6-hexahydro-azepino[4,5-b]indol...)
Affinity DataEC50:  7.70nMAssay Description:Agonist activity at human 5HT2C receptor expressed in HEK293 cells assessed as induction of intracellular calcium release measured for 90 secs by flu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50130095(6-Methyl-1,2,3,4,5,6-hexahydro-azepino[4,5-b]indol...)
Affinity DataEC50:  23nMAssay Description:Agonist activity at human 5HT2A receptor expressed in HEK293 cells assessed as induction of intracellular calcium release measured for 90 secs by flu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed