BDBM50131225 CHEMBL3634769::US9260425, 515
SMILES CCn1cncc(-c2cc3c(n[nH]c3cn2)-c2cccc(n2)N2CCNCC2)c1=O
InChI Key InChIKey=BAUZKJYZGGFFLL-UHFFFAOYSA-N
Data 4 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50131225
Affinity DataKi: 0.0150nMpH: 7.2Assay Description:PIM-1, PIM-2, and PIM-3 enzymes were generated as fusion proteins expressed in bacteria and purified by IMAC column chromatography (Sun, X., Chiu, J....More data for this Ligand-Target Pair
Affinity DataKi: 0.0150nMAssay Description:Inhibition of Pim1 (unknown origin) using 5FAM-ARKRRRHPSGPPTA as substrate after 90 minsMore data for this Ligand-Target Pair
Affinity DataKi: 0.0700nMAssay Description:Inhibition of Pim3 (unknown origin) using 5FAM-ARKRRRHPSGPPTA as substrate after 90 minsMore data for this Ligand-Target Pair
Affinity DataKi: 0.145nMAssay Description:Inhibition of Pim2 (unknown origin) using 5FAM-ARKRRRHPSGPPTA as substrate after 90 minsMore data for this Ligand-Target Pair