BDBM50131377 CHEMBL3634781::US9260425, 162
SMILES C1CN(CCN1)c1cccc(n1)-c1n[nH]c2cnc(cc12)-c1cccnc1
InChI Key InChIKey=XVJJTRNNWYKRTH-UHFFFAOYSA-N
Data 4 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50131377
Affinity DataKi: 0.0100nMAssay Description:Inhibition of Pim3 (unknown origin) using 5FAM-ARKRRRHPSGPPTA as substrate after 90 minsMore data for this Ligand-Target Pair
Affinity DataKi: 0.0370nMpH: 7.2Assay Description:PIM-1, PIM-2, and PIM-3 enzymes were generated as fusion proteins expressed in bacteria and purified by IMAC column chromatography (Sun, X., Chiu, J....More data for this Ligand-Target Pair
Affinity DataKi: 0.0400nMAssay Description:Inhibition of Pim1 (unknown origin) using 5FAM-ARKRRRHPSGPPTA as substrate after 90 minsMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Inhibition of Pim2 (unknown origin) using 5FAM-ARKRRRHPSGPPTA as substrate after 90 minsMore data for this Ligand-Target Pair