BDBM50131891 3-Methyl-4-oxo-2-phenyl-4H-chromene-8-carboxylic acid (3-{4-[2-(3-nitrooxy-propoxy)-phenyl]-piperazin-1-yl}-propyl)-amide::CHEMBL338029

SMILES Cc1c(oc2c(cccc2c1=O)C(=O)NCCCN1CCN(CC1)c1ccccc1OCCCO[N+]([O-])=O)-c1ccccc1

InChI Key InChIKey=OTPCOGQCPMOGMX-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50131891   

TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50131891(3-Methyl-4-oxo-2-phenyl-4H-chromene-8-carboxylic a...)
Affinity DataKi:  0.0940nMAssay Description:Inhibition of [3H]-prazosin binding to cloned human Alpha-1A adrenergic receptor in CHO-cells (chinese hamster ovary cells)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50131891(3-Methyl-4-oxo-2-phenyl-4H-chromene-8-carboxylic a...)
Affinity DataKi:  1.20nMAssay Description:Inhibition of [3H]-prazosin binding to cloned human Alpha-1B adrenergic receptor in CHO-cells (chinese hamster ovary cells)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50131891(3-Methyl-4-oxo-2-phenyl-4H-chromene-8-carboxylic a...)
Affinity DataKi:  3.5nMAssay Description:Inhibition of [3H]-prazosin binding to cloned human Alpha-1D adrenergic receptor in CHO-cells (chinese hamster ovary cells)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50131891(3-Methyl-4-oxo-2-phenyl-4H-chromene-8-carboxylic a...)
Affinity DataKi:  7.20nMAssay Description:Inhibition of [3H]-8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor serotonergic receptor in human HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed