BDBM50133135 9-Fluoro-2,2,4-trimethyl-5-[1-(2-methylsulfanyl-phenyl)-meth-(Z)-ylidene]-2,5-dihydro-1H-6-oxa-1-aza-chrysene::CHEMBL422444
SMILES CSc1ccccc1\C=C1/Oc2ccc(F)cc2-c2ccc3NC(C)(C)C=C(C)c3c12
InChI Key InChIKey=ISFPMZBOTSJQDY-QRVIBDJDSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50133135
Affinity DataKi: 0.590nMAssay Description:Binding affinity towards human progesterone receptor A isoform using progesterone as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 386nMAssay Description:Inhibition of Dexamethasone binding to human glucocorticoid receptor expressed in baculovirus SF-12 cellsMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of DHT binding to human androgen receptor expressed in baculovirus SF-12 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 41nMAssay Description:Agonistic activity against human progesterone receptor in T47D breast cancer cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 6.20nMAssay Description:Agonistic activity against human progesterone receptor in CV-1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 860nMAssay Description:Inhibition of human glucocorticoid receptor at 10e-12 to 10e-5 MMore data for this Ligand-Target Pair