BDBM50135454 (2E,4E,6Z)-7-(3-Isopropyl-5-pentafluoroethyl-2-propoxy-phenyl)-3-methyl-octa-2,4,6-trienoic acid::CHEMBL132568

SMILES CCCOc1c(cc(cc1\C(C)=C/C=C/C(/C)=C/C(O)=O)C(F)(F)C(F)(F)F)C(C)C

InChI Key InChIKey=CBZASUFZCYJPCI-ZHOIUTETSA-N

Data  6 KI  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50135454   

TargetRetinoic acid receptor RXR-beta(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50135454((2E,4E,6Z)-7-(3-Isopropyl-5-pentafluoroethyl-2-pro...)
Affinity DataKi:  17nMAssay Description:Displacement of [3H]-9-cis-RA from RXR beta receptor in CV-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50135454((2E,4E,6Z)-7-(3-Isopropyl-5-pentafluoroethyl-2-pro...)
Affinity DataKi:  26nMAssay Description:Binding affinity against RXR alpha receptor using [3H]-9-cis-RA as radioligand in CV-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-gamma(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50135454((2E,4E,6Z)-7-(3-Isopropyl-5-pentafluoroethyl-2-pro...)
Affinity DataKi:  28nMAssay Description:Binding affinity against RXR gamma receptor using [3H]-9-cis-RA as radioligand in CV-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor gamma(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50135454((2E,4E,6Z)-7-(3-Isopropyl-5-pentafluoroethyl-2-pro...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity against RAR gamma receptor using [3H]-ATRA as radioligand in CV-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor beta(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50135454((2E,4E,6Z)-7-(3-Isopropyl-5-pentafluoroethyl-2-pro...)
Affinity DataKi:  1.98E+3nMAssay Description:Binding affinity against RAR beta receptor using [3H]-ATRA as radioligand in CV-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor alpha(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50135454((2E,4E,6Z)-7-(3-Isopropyl-5-pentafluoroethyl-2-pro...)
Affinity DataKi:  2.50E+3nMAssay Description:Binding affinity against RAR alpha receptor using [3H]-ATRA as radioligand in CV-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50135454((2E,4E,6Z)-7-(3-Isopropyl-5-pentafluoroethyl-2-pro...)
Affinity DataEC50:  2.70nMAssay Description:In vitro agonistic activity against PPAR gamma along with 100 nM BRL49653More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50135454((2E,4E,6Z)-7-(3-Isopropyl-5-pentafluoroethyl-2-pro...)
Affinity DataEC50:  59nMAssay Description:In vitro agonist efficacy against PPAR gamma along with 100 nM BRL49653More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50135454((2E,4E,6Z)-7-(3-Isopropyl-5-pentafluoroethyl-2-pro...)
Affinity DataIC50:  5.10nMAssay Description:In vitro anatagonist activity against RXR alpha in CV-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed