BDBM50135752 (2E)-N-hydroxy-3-[1-methyl-4-(phenylacetyl)-1H-pyrrol-2-yl]prop-2-enamide::(E)-N-Hydroxy-3-(1-methyl-4-phenylacetyl-1H-pyrrol-2-yl)-acrylamide::CHEMBL12760::N-Hydroxy-3-((E)-1-methyl-4-phenylacetyl-1H-pyrrol-2-yl)-acrylamide::N-Hydroxy-3-(1-methyl-4-phenylacetyl-1H-pyrrol-2-yl)-acrylamide

SMILES Cn1cc(cc1C=CC(=O)NO)C(=O)Cc1ccccc1

InChI Key InChIKey=UFQOXIMRSMFQRI-UHFFFAOYSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50135752   

TargetHistone deacetylase 2b(Zea mays)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50135752((2E)-N-hydroxy-3-[1-methyl-4-(phenylacetyl)-1H-pyr...)
Affinity DataIC50:  100nMAssay Description:Inhibitory concentration against histone deacetylase HD2 enzyme.Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2b(Zea mays)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50135752((2E)-N-hydroxy-3-[1-methyl-4-(phenylacetyl)-1H-pyr...)
Affinity DataIC50:  100nMAssay Description:Inhibitory activity against maize Histone deacetylase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Mus musculus (Mouse))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50135752((2E)-N-hydroxy-3-[1-methyl-4-(phenylacetyl)-1H-pyr...)
Affinity DataIC50:  513nMAssay Description:Inhibitory activity against mouse Histone deacetylase 1 (HDAC1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2b(Zea mays)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50135752((2E)-N-hydroxy-3-[1-methyl-4-(phenylacetyl)-1H-pyr...)
Affinity DataIC50:  100nMAssay Description:Inhibitory concentration against histone deacetylase HD2 enzyme.Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed