BDBM50137677 4-(3,4,5-Trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-ylamino)-benzenesulfonamide::CHEMBL72447::N-(p-sulfamoylphenyl)-alpha-glycopyranosylamine, 1::N-(p-sulfamoylphenyl)-alpha-glycopyranosylamine, 2::N-(p-sulfamoylphenyl)-alpha-glycopyranosylamine, 3

SMILES NS(=O)(=O)c1ccc(NC2OC(CO)C(O)C(O)C2O)cc1

InChI Key InChIKey=RMCYKIOWPVOBJX-UHFFFAOYSA-N

Data  9 KI

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50137677   

TargetCarbonic anhydrase 6(Homo sapiens (Human))
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM50137677(4-(3,4,5-Trihydroxy-6-hydroxymethyl-tetrahydro-pyr...)
Affinity DataKi:  0.640nM ΔG°:  -12.3kcal/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 6(Homo sapiens (Human))
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM50137677(4-(3,4,5-Trihydroxy-6-hydroxymethyl-tetrahydro-pyr...)
Affinity DataKi:  10.1nM ΔG°:  -10.7kcal/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM50137677(4-(3,4,5-Trihydroxy-6-hydroxymethyl-tetrahydro-pyr...)
Affinity DataKi:  18nM ΔG°:  -10.4kcal/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM50137677(4-(3,4,5-Trihydroxy-6-hydroxymethyl-tetrahydro-pyr...)
Affinity DataKi:  23nM ΔG°:  -10.2kcal/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM50137677(4-(3,4,5-Trihydroxy-6-hydroxymethyl-tetrahydro-pyr...)
Affinity DataKi:  25nM ΔG°:  -10.2kcal/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 6(Homo sapiens (Human))
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM50137677(4-(3,4,5-Trihydroxy-6-hydroxymethyl-tetrahydro-pyr...)
Affinity DataKi:  34.1nM ΔG°:  -10.0kcal/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM50137677(4-(3,4,5-Trihydroxy-6-hydroxymethyl-tetrahydro-pyr...)
Affinity DataKi:  930nM ΔG°:  -8.08kcal/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM50137677(4-(3,4,5-Trihydroxy-6-hydroxymethyl-tetrahydro-pyr...)
Affinity DataKi:  1.00E+3nM ΔG°:  -8.04kcal/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Institut Des BiomolÉCules Max Mousseron (Ibmm)

LigandPNGBDBM50137677(4-(3,4,5-Trihydroxy-6-hydroxymethyl-tetrahydro-pyr...)
Affinity DataKi:  1.20E+3nM ΔG°:  -7.94kcal/molepH: 7.5 T: 2°CAssay Description:Inhibition assay using carbonic anhydrases with an SX.18MV-R, a stopped-flow instrument from Applied Photophysics was used for assaying the CA cataly...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed