BDBM50139957 2beta-carbomethoxy-3beta-[4'-((Z)-2-iodoethenyl)phenyl]nortropane::3-[4-((Z)-2-Iodo-vinyl)-phenyl]-8-aza-bicyclo[3.2.1]octane-2-carboxylic acid methyl ester::CHEMBL428706

SMILES COC(=O)C1C2CCC(CC1c1ccc(\C=C/I)cc1)N2

InChI Key InChIKey=GZWPHROGQGOESZ-HJWRWDBZSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50139957   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50139957(2beta-carbomethoxy-3beta-[4'-((Z)-2-iodoethenyl)ph...)
Affinity DataKi:  0.0400nMAssay Description:Displacement of [3H]citalopram from SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50139957(2beta-carbomethoxy-3beta-[4'-((Z)-2-iodoethenyl)ph...)
Affinity DataKi:  0.0500nMAssay Description:Inhibition of [125I]-RTI-55 binding to human serotonin transporter expressed in human embryonic kidney cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50139957(2beta-carbomethoxy-3beta-[4'-((Z)-2-iodoethenyl)ph...)
Affinity DataKi:  0.0500nMAssay Description:Inhibition of [125I]-RTI-55 binding to human serotonin transporter expressed in human embryonic kidney cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50139957(2beta-carbomethoxy-3beta-[4'-((Z)-2-iodoethenyl)ph...)
Affinity DataKi:  3.5nMAssay Description:In vitro binding affinity against human dopamine transporter in dog kidney cell line by using [125I]-RTI-55 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50139957(2beta-carbomethoxy-3beta-[4'-((Z)-2-iodoethenyl)ph...)
Affinity DataKi:  6nMAssay Description:Displacement of [123I]RTI-55 from DATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50139957(2beta-carbomethoxy-3beta-[4'-((Z)-2-iodoethenyl)ph...)
Affinity DataKi:  15nMAssay Description:In vitro binding affinity against human dopamine transporter in dog kidney cell line using [125I]-RTI-55 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50139957(2beta-carbomethoxy-3beta-[4'-((Z)-2-iodoethenyl)ph...)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]nisoxetine from NETMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Emory University

Curated by ChEMBL
LigandPNGBDBM50139957(2beta-carbomethoxy-3beta-[4'-((Z)-2-iodoethenyl)ph...)
Affinity DataKi:  24nMAssay Description:In vitro binding affinity against human norepinephrin transporter in human embryonic kidney cell line using [125I]-RTI-55 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed