BDBM50140241 Allopurinol::Aloral::Aluline 100::Aluline 300::BW-56-158::BW-56158::CHEBI:40279::Caplenal::Cosuric::Hamarin 100::Hamarin 300::Ledopur::Lopurin::US11161835, Compound Allopurinol::Uricto::Xanthomax-100::Xanthomax-300::Zyloprim::Zyloric::Zyloric-300
SMILES O=c1[nH]cnc2[nH]ncc12
InChI Key InChIKey=OFCNXPDARWKPPY-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 58 hits for monomerid = 50140241
Affinity DataKi: 100nMAssay Description:Inhibition of human xanthine oxidaseMore data for this Ligand-Target Pair
Affinity DataKi: 700nMAssay Description:Competitive inhibition of xanthine oxidase (unknown origin) assessed as inhibitory constant of enzyme-substrate complex using xanthine as substrate a...More data for this Ligand-Target Pair
Affinity DataKi: 700nMAssay Description:Inhibition of xanthine oxidase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.39E+4nMAssay Description:Inhibition of Shigella dysenteriae type 1 Shiga toxin A subunit in African green monkey Vero cells assessed as inhibition of Stx-induced cytotoxicity...More data for this Ligand-Target Pair
Affinity DataIC50: 9.80E+3nMAssay Description:Inhibition of bovine xanthine oxidase assessed as reduction in uric acid levels using xanthine as substrate after 120 mins by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 3.61E+3nMAssay Description:Inhibition of Xanthine oxidase (unknown origin) using xanthine as substrate preincubated for 3 mins followed by substrate addition measured every 15 ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of bovine xanthine oxidase using xanthine as substrate preincubated for 10 mins followed by substrate addition measured for 15 mins by spe...More data for this Ligand-Target Pair
Affinity DataIC50: 1.96E+4nMAssay Description:Inhibition of bovine milk xanthine oxidase pre-incubated for 30 mins followed by xanthine addition and measured every 30 secs for 5 mins by spectroph...More data for this Ligand-Target Pair
Affinity DataIC50: 260nMAssay Description:Inhibition of bovine milk xanthine-oxygen reductase using xanthine as substrate by spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.58E+5nMAssay Description:Inhibition of bovine milk xanthine oxidase assessed using xanthine as substrate after 10 mins by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8.31E+3nMAssay Description:Inhibition of bovine milk xanthine oxidase assessed as reduction in uric acid formation using xanthine as substrate preincubated for 5 mins followed ...More data for this Ligand-Target Pair
Affinity DataKd: 0.540nMAssay Description:Binding affinity to bovine milk xanthine oxidase assessed as reduction in conversion of 4-HPP to 4,6-diHPP by measuring cytochrome c reduction by spe...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of xanthine oxidase (unknown origin) assessed as reduction in uric acid formation using xanthine as substrate after 10 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.07E+4nMAssay Description:Inhibition of xanthine oxidase (unknown origin) assessed as reduction in uric acid formation using xanthine as substrate after 4 mins by UV-Vis spect...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of xanthine oxidase (unknown origin) using xanthine as substrate measured at every 1 mins up to 5 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.43E+4nMAssay Description:Inhibition of xanthine oxidase (unknown origin) by SAR analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 3.53E+3nMAssay Description:Inhibition of bovine milk xanthine oxidase assessed as reduction in uric acid formation using xanthine as substrate preincubated for 3 hrs followed b...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of xanthine oxidase (unknown origin) assessed as reduction in uric acid formation using xanthine as substrate after 10 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.53E+3nMAssay Description:Inhibition of bovine milk xanthine oxidase assessed as reduction in uric acid formation using xanthine as substrate preincubated for 3 hrs followed b...More data for this Ligand-Target Pair
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.33E+5nMAssay Description:The compound was tested on recombinant human alpha4-beta2 cell lines of Human embryonic kidney for nicotinic acetylcholine receptor agonist functiona...More data for this Ligand-Target Pair
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
Affinity DataIC50: 7.56E+3nMAssay Description:Inhibition of bovine xanthine oxidase assessed as reduction in uric acid production using xanthine as substrate preincubated for 10 mins followed by ...More data for this Ligand-Target Pair
Affinity DataIC50: 5.02E+4nMAssay Description:Inhibition of xanthine oxidase (unknown origin) using xanthine as substrate preincubated for 15 mins followed by substrate addition by spectrophotome...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of xanthine oxidase (unknown origin) using xanthine as substrate pretreated for 10 mins followed by substrate addition measured every 2 mi...More data for this Ligand-Target Pair
Affinity DataIC50: 8.50E+3nMAssay Description:Antagonistic activity against the P2X7 ion channelMore data for this Ligand-Target Pair
Affinity DataIC50: 3.17E+3nMAssay Description:Inhibition of xanthine oxidase (unknown origin) at 30 uM using xanthine as substrate preincubated for 5 mins followed by substrate addition measured ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of bovine milk xanthine oxidase using xanthine as substrate pretreated for 15 mins followed by substrate addition measured after 8 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 250nMAssay Description:Inhibition of bovine milk xanthine oxidase using xanthine as substrate preincubated for 15 mins followed by substrate addition measured after 30 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of cow milk xanthine oxidoreductase using hypoxanthine by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of Xanthine oxidase (unknown origin) using xanthine as substrate preincubated for 1 to 5 mins followed by substrate additionMore data for this Ligand-Target Pair
Affinity DataIC50: 1.06E+4nMAssay Description:Inhibition of bovine xanthine oxidase using xanthine as substrate preincubated for 3 mins followed by substrate addition and measured for every 15 se...More data for this Ligand-Target Pair
Affinity DataIC50: 3.16E+4nMAssay Description:Inhibition of xanthine oxidase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of Oryctolagus cuniculus (rabbit) AOX in liver cytosolMore data for this Ligand-Target Pair
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of Agaricus bisporus (mushroom) tyrosinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 3.89E+3nMAssay Description:Inhibition of xanthine oxidase- mediated uric acid formation after 5 mins by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 1.17E+4nMAssay Description:Inhibition of xanthine oxidase (unknown origin) using xanthine as substrate assessed as uric acid formation preincubated for 5 mins followed by subst...More data for this Ligand-Target Pair
Affinity DataIC50: 7.59E+3nMAssay Description:Inhibition of bovine xanthine oxidase assessed as reduction in uric acid formation using xanthine as substrate preincubated with enzyme for 15 mins f...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of bovine milk xanthine oxidase assessed as reduction in uric acid production using xanthine as substrate after 10 mins by HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 6.43E+3nMAssay Description:Inhibition of bovine xanthine oxidase assessed as reduction in uric acid formation preincubated for 5 mins followed by xanthine addition and measured...More data for this Ligand-Target Pair
Affinity DataIC50: 7.59E+3nMAssay Description:Inhibition of bovine milk xanthine oxidase using xanthine as substrate incubated for 15 mins followed by substrate addition and measured at 30 sec in...More data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of xanthine oxidase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.50E+3nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
Affinity DataIC50: 7.59E+3nMAssay Description:Inhibition of bovine xanthine oxidase assessed as reduction in uric acid formation using xanthine as substrate preincubated for 25 mins followed by s...More data for this Ligand-Target Pair
Affinity DataIC50: 2.52E+3nMAssay Description:Inhibition of bovine milk xanthine oxidase assessed as reduction in uric acid formation using xanthine as substrate measured for 20 mins by microplat...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan MP: ...More data for this Ligand-Target Pair
Affinity DataIC50: 5.46E+3nMAssay Description:Inhibition of bovine milk xanthine oxidase assessed as reduction in uric acid formation using xanthine as substrate preincubated for 15 mins followed...More data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibition of xanthine oxidase (unknown origin) at 10 uM using xanthine as substrateMore data for this Ligand-Target Pair
Affinity DataKd: 7.70E+4nMAssay Description:Binding affinity to human wild type adenosine A2A receptor expressed in Expi293F cells assessed as dissociation constant by surface plasmon resonance...More data for this Ligand-Target Pair