BDBM50146536 4-(6-Chloro-naphthalene-2-sulfonyl)-1-(5-methyl-4,5,6,7-tetrahydro-thiazolo[5,4-c]pyridine-2-carbonyl)-piperazine-2-carboxylic acid amide::CHEMBL100751

SMILES CN1CCc2nc(sc2C1)C(=O)N1CCN(CC1C(N)=O)S(=O)(=O)c1ccc2cc(Cl)ccc2c1

InChI Key InChIKey=OVHHNKPYYVQCLN-UHFFFAOYSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50146536   

TargetCoagulation factor X(Homo sapiens (Human))
Daiichi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146536(4-(6-Chloro-naphthalene-2-sulfonyl)-1-(5-methyl-4,...)
Affinity DataIC50:  24nMAssay Description:In vitro inhibitory activity of the compound against human Coagulation factor XMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Daiichi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146536(4-(6-Chloro-naphthalene-2-sulfonyl)-1-(5-methyl-4,...)
Affinity DataIC50:  1.00E+6nMAssay Description:Concentration required to inhibit thrombin activity by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Daiichi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146536(4-(6-Chloro-naphthalene-2-sulfonyl)-1-(5-methyl-4,...)
Affinity DataIC50:  24nMAssay Description:Inhibitory concentration against Coagulation factor XMore data for this Ligand-Target Pair
TargetProthrombin(Homo sapiens (Human))
Daiichi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50146536(4-(6-Chloro-naphthalene-2-sulfonyl)-1-(5-methyl-4,...)
Affinity DataIC50:  1.00E+3nMAssay Description:In vitro inhibitory activity of the compound against human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed