BDBM50148479 CHEMBL3770259

SMILES COc1ccc(Oc2cc3n(C)c(=O)n(C)c3cc2NS(=O)(=O)c2ccccc2)cc1

InChI Key InChIKey=KQJPZLNOKCNFSE-UHFFFAOYSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50148479   

TargetTranscription intermediary factor 1-alpha(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50148479(CHEMBL3770259)
Affinity DataIC50:  730nMAssay Description:Inhibition of N-terminal His6-SUMO-1-tagged recombinant human TRIM24 bromodomain expressed in Escherichia coli BL21(DE3)-R3-pRARE2 cells by Alpha Scr...More data for this Ligand-Target Pair
TargetTranscription intermediary factor 1-alpha(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50148479(CHEMBL3770259)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of KDM5C (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50148479(CHEMBL3770259)
Affinity DataIC50:  2.77E+3nMAssay Description:Inhibition of BRPF2 BRD1 (unknown origin) by Alpha Screen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeregrin(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50148479(CHEMBL3770259)
Affinity DataIC50:  660nMAssay Description:Inhibition of BRPF1B (unknown origin) by Alpha Screen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed