BDBM50150086 CHEMBL127171::[3-(5-Fluoro-1H-indol-3-yl)-propyl]-[2-(5-fluoro-2-methoxy-phenoxy)-ethyl]-amine
SMILES COc1ccc(F)cc1OCCNCCCc1c[nH]c2ccc(F)cc12
InChI Key InChIKey=JVZKOTRMFQSGLN-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50150086
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataKi: 1.36nMAssay Description:Binding affinity against serotonin transporter in rat cortical tissues using radioligand [3H]-paroxetineMore data for this Ligand-Target Pair
Affinity DataKi: 35nMAssay Description:Binding affinity against human 5-hydroxytryptamine 1A receptor in CHO cells labeled with [3H]-8-OH-DPAT radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 20.5nMAssay Description:Inhibition concentration against [3H]-5-HT uptake by human serotonin transporter in JAR cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 0.340nMAssay Description:Effective concentration against binding of radioligand [35]GTPgammaS in CHO cells expressing human 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 4.70nMAssay Description:Effective concentration against human 5-hydroxytryptamine 1A receptor using cAMP as radioligand in CHO cellsMore data for this Ligand-Target Pair