BDBM50150789 2,6-dibromophenol::CHEMBL111507

SMILES Oc1c(Br)cccc1Br

InChI Key InChIKey=SSIZLKDLDKIHEV-UHFFFAOYSA-N

Data  1 KI  2 IC50  2 EC50

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50150789   

Target2,6-dichloro-p-hydroquinone 1,2-dioxygenase(Sphingobium chlorophenolicum)
Whitman College

LigandPNGBDBM50150789(2,6-dibromophenol | CHEMBL111507)
Affinity DataKi:  1.30E+4nMAssay Description:The rate of the enzymatic reaction was determined by measuring product formation by a spectrophotometric assay developed by Xun and co-worker with mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
University Of Chicago Medical Center

Curated by ChEMBL
LigandPNGBDBM50150789(2,6-dibromophenol | CHEMBL111507)
Affinity DataEC50:  1.00E+8nMAssay Description:Potentiation of GABA responses at human Gamma-aminobutyric acid A receptor alpha-1-beta-2-gamma-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
University Of Chicago Medical Center

Curated by ChEMBL
LigandPNGBDBM50150789(2,6-dibromophenol | CHEMBL111507)
Affinity DataEC50:  1.00E+8nMAssay Description:Direct activation of human Gamma-aminobutyric acid A receptor alpha-1-beta-2-gamma-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50150789(2,6-dibromophenol | CHEMBL111507)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory effect on human reticulocyte 15-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50150789(2,6-dibromophenol | CHEMBL111507)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory effect on human platelet 12-lipoxygenaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed