BDBM50157107 1-Benzooxazol-2-yl-6-phenyl-hexan-1-one::CHEMBL366907

SMILES O=C(CCCCCc1ccccc1)c1nc2ccccc2o1

InChI Key InChIKey=PCLBCMUYLOBYMW-UHFFFAOYSA-N

Data  3 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50157107   

TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50157107(1-Benzooxazol-2-yl-6-phenyl-hexan-1-one | CHEMBL36...)
Affinity DataKi:  220nMAssay Description:Binding affinity against purified rat Fatty-acid amide hydrolase (FAAH) expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Mus musculus (mouse))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50157107(1-Benzooxazol-2-yl-6-phenyl-hexan-1-one | CHEMBL36...)
Affinity DataKi:  220nMAssay Description:Inhibitor affinity of the compound towards enzymes of class serine hydrolase was determined using biotin or fluorescent as radioligand (FP-biotin or ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50157107(1-Benzooxazol-2-yl-6-phenyl-hexan-1-one | CHEMBL36...)
Affinity DataKi:  220nMAssay Description:Inhibitory constant determined against recombinant Fatty-acid amide hydrolase from rat expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol lipase-alpha(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50157107(1-Benzooxazol-2-yl-6-phenyl-hexan-1-one | CHEMBL36...)
Affinity DataIC50:  3.63E+3nMAssay Description:Inhibition of full-length human DAGLalpha expressed in HEK293T cell membranes using para-nitrophenylbutyrate by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLiver carboxylesterase 1(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50157107(1-Benzooxazol-2-yl-6-phenyl-hexan-1-one | CHEMBL36...)
Affinity DataIC50:  20nMAssay Description:Inhibitory concentration against Triacylglycerol hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50157107(1-Benzooxazol-2-yl-6-phenyl-hexan-1-one | CHEMBL36...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibitory concentration against Fatty-acid amide hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50157107(1-Benzooxazol-2-yl-6-phenyl-hexan-1-one | CHEMBL36...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibitory concentration of fatty acid amide hydrolase using FP-Rh radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLiver carboxylesterase 1(Homo sapiens (Human))
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50157107(1-Benzooxazol-2-yl-6-phenyl-hexan-1-one | CHEMBL36...)
Affinity DataIC50:  20nMAssay Description:Inhibitory concentration of triacylgylcerol hydrolase using FP-Rh radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed