BDBM50159169 (3S,4aR,4bS,6S,8R,8aR,10aS)-6-Acetoxy-3-furan-3-yl-4a,8a-dimethyl-1,5-dioxo-dodecahydro-2-oxa-phenanthrene-8-carboxylic acid methyl ester::CHEMBL435108::Salvinorin A (ester)

SMILES COC(=O)[C@@H]1C[C@H](OC(C)=O)C(=O)[C@H]2[C@@]1(C)CC[C@@H]1C(=O)O[C@@H](C[C@]21C)c1ccoc1

InChI Key InChIKey=OBSYBRPAKCASQB-FBCTZMOOSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50159169   

TargetKappa-type opioid receptor(Homo sapiens (Human))
Mclean Hospital

Curated by ChEMBL
LigandPNGBDBM50159169((3S,4aR,4bS,6S,8R,8aR,10aS)-6-Acetoxy-3-furan-3-yl...)
Affinity DataKi:  140nMAssay Description:Inhibition of [3H]diprenorphine binding to human KOR expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
The University Of Melbourne

Curated by PDSP Ki Database
LigandPNGBDBM50159169((3S,4aR,4bS,6S,8R,8aR,10aS)-6-Acetoxy-3-furan-3-yl...)
Affinity DataKi:  163nMAssay Description:Inhibition of [3H]-U-69,593 binding to rat opioid receptor kappa 1 expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Mclean Hospital

Curated by ChEMBL
LigandPNGBDBM50159169((3S,4aR,4bS,6S,8R,8aR,10aS)-6-Acetoxy-3-furan-3-yl...)
Affinity DataEC50:  531nMAssay Description:Enhancement of [35S]GTPgammaS binding to human KOR expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed