BDBM50164201 12-(6-aminomethyl-5,5-difluoro-3,4-dihydroxytetrahydro-2H-2-pyranyl)-2,3,9,10-tetrafluoro-6,7,12,13-tetrahydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7-dione::CHEMBL370476

SMILES NCC1OC(C(O)C(O)C1(F)F)n1c2cc(F)c(F)cc2c2c3C(=O)NC(=O)c3c3c4cc(F)c(F)cc4[nH]c3c12

InChI Key InChIKey=AOMCGGJSCBYDCG-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50164201   

TargetDNA topoisomerase 1(Homo sapiens (Human))
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50164201(12-(6-aminomethyl-5,5-difluoro-3,4-dihydroxytetrah...)
Affinity DataEC50:  8nMAssay Description:Topoisomerase I activity for single-strand breaks in the DNA substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed