BDBM50164392 CHEMBL3797818

SMILES CCNC(=O)c1c(C)sc2nc(Cc3cccc(c3F)C(F)(F)F)cc(=O)n12

InChI Key InChIKey=ZBZNBRLJRWPWRY-UHFFFAOYSA-N

Data  3 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50164392   

TargetGlutamate receptor ionotropic, NMDA 1/2A(Homo sapiens (Human))
Pharmaron-Beijing

Curated by ChEMBL
LigandPNGBDBM50164392(CHEMBL3797818)
Affinity DataEC50:  1.20E+3nMAssay Description:Positive allosteric modulation of GluN1/GluN2A NMDAR (unknown origin) expressed in Dox-inducible cells measured every 5 mins by BD calcium indicator ...More data for this Ligand-Target Pair
TargetGlutamate receptor 2(Homo sapiens (Human))
Pharmaron-Beijing

Curated by ChEMBL
LigandPNGBDBM50164392(CHEMBL3797818)
Affinity DataEC50:  2.94E+4nMAssay Description:Positive allosteric modulation of human GluA2 AMPAR flop isomer expressed in Dox-inducible cells measured every 5 mins by BD calcium indicator dye ba...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 2(Homo sapiens (Human))
Pharmaron-Beijing

Curated by ChEMBL
LigandPNGBDBM50164392(CHEMBL3797818)
Affinity DataEC50:  2.83E+4nMAssay Description:Positive allosteric modulation of human GluA2 AMPAR flip isomer expressed in Dox-inducible cells measured every 5 mins by BD calcium indicator dye ba...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed