BDBM50165420 CHEMBL197509::[(S)-1-((R)-1-Phenyl-ethylaminooxalyl)-pentyl]-carbamic acid adamantan-2-yl ester

SMILES CCCC[C@H](NC(=O)OC1C2CC3CC(C2)CC1C3)C(=O)C(=O)N[C@H](C)c1ccccc1

InChI Key InChIKey=QFJGHQXICGBKTL-GFAXYUDLSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50165420   

TargetPro-cathepsin H(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50165420(CHEMBL197509 | [(S)-1-((R)-1-Phenyl-ethylaminooxal...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibitory concentration against human cathepsin H by fluorescence assay using 50 uM L-Arg-b-naphthalamideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50165420(CHEMBL197509 | [(S)-1-((R)-1-Phenyl-ethylaminooxal...)
Affinity DataIC50:  7.20nMAssay Description:Inhibitory concentration against human cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50165420(CHEMBL197509 | [(S)-1-((R)-1-Phenyl-ethylaminooxal...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibitory concentration against human cathepsin B by fluorescence assay using 10 uM Cbz-Phe-Arg-AMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin L2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50165420(CHEMBL197509 | [(S)-1-((R)-1-Phenyl-ethylaminooxal...)
Affinity DataIC50:  390nMAssay Description:Inhibitory concentration against human cathepsin V by fluorescence assay using 2 uM Cbz-Phe-Arg-AMC More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50165420(CHEMBL197509 | [(S)-1-((R)-1-Phenyl-ethylaminooxal...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibitory concentration against human cathepsin L by fluorescence assay using 5 uM Cbz-Phe-Arg-AMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50165420(CHEMBL197509 | [(S)-1-((R)-1-Phenyl-ethylaminooxal...)
Affinity DataIC50:  16nMAssay Description:Inhibitory concentration against human cathepsin S by fluorescence assay using 10 uM Cbz-Val-Val-Arg-AMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed