BDBM50165426 CHEMBL196298::[(S)-1-((R)-1-Phenyl-ethylaminooxalyl)-pentyl]-carbamic acid bicyclo[2.2.1]hept-2-yl ester

SMILES CCCC[C@H](NC(=O)OC1CC2CCC1C2)C(=O)C(=O)N[C@H](C)c1ccccc1

InChI Key InChIKey=HMVXEHSUUNUEBL-BEMVKYSYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50165426   

TargetPro-cathepsin H(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50165426(CHEMBL196298 | [(S)-1-((R)-1-Phenyl-ethylaminooxal...)
Affinity DataIC50: >1.30E+4nMAssay Description:Inhibitory concentration against human cathepsin H by fluorescence assay using 50 uM L-Arg-b-naphthalamideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin L2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50165426(CHEMBL196298 | [(S)-1-((R)-1-Phenyl-ethylaminooxal...)
Affinity DataIC50:  190nMAssay Description:Inhibitory concentration against human cathepsin V by fluorescence assay using 2 uM Cbz-Phe-Arg-AMC More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50165426(CHEMBL196298 | [(S)-1-((R)-1-Phenyl-ethylaminooxal...)
Affinity DataIC50:  26nMAssay Description:Inhibitory concentration against human cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50165426(CHEMBL196298 | [(S)-1-((R)-1-Phenyl-ethylaminooxal...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibitory concentration against human cathepsin L by fluorescence assay using 5 uM Cbz-Phe-Arg-AMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50165426(CHEMBL196298 | [(S)-1-((R)-1-Phenyl-ethylaminooxal...)
Affinity DataIC50:  19nMAssay Description:Inhibitory concentration against human cathepsin S by fluorescence assay using 10 uM Cbz-Val-Val-Arg-AMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50165426(CHEMBL196298 | [(S)-1-((R)-1-Phenyl-ethylaminooxal...)
Affinity DataIC50: >1.30E+4nMAssay Description:Inhibitory concentration against human cathepsin B by fluorescence assay using 10 uM Cbz-Phe-Arg-AMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed