BDBM50172190 (4S,4aR)-6-Hydroxy-4a-methyl-1-(S)-methyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-1-carboxylic acid ((1R,2R,3R,5S)-2,6,6-trimethyl-bicyclo[3.1.1]hept-3-yl)-amide::CHEMBL382942

SMILES C[C@@H]1[C@H]2C[C@@H](C[C@H]1NC(=O)[C@@]1(C)CCC[C@@]3(C)[C@H]1CCc1ccc(O)cc31)C2(C)C

InChI Key InChIKey=AWFKUZKMHLKRBA-LRZFQQLUSA-N

Data  2 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50172190   

TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172190((4S,4aR)-6-Hydroxy-4a-methyl-1-(S)-methyl-1,2,3,4,...)
Affinity DataEC50: >5.00E+4nMAssay Description:Effective concentration in recombinant human LXRbeta ligand binding domain in homogeneous time-resolved fluorescence assay More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172190((4S,4aR)-6-Hydroxy-4a-methyl-1-(S)-methyl-1,2,3,4,...)
Affinity DataEC50:  1.70E+3nMAssay Description:Effective concentration in transactivation assay using a chimeric LXR construct in HEK-293 cells for LXRalpha receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172190((4S,4aR)-6-Hydroxy-4a-methyl-1-(S)-methyl-1,2,3,4,...)
Affinity DataEC50:  280nMAssay Description:Effective concentration in transactivation assay using a chimeric LXR construct in HEK293 cells for LXRalpha receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172190((4S,4aR)-6-Hydroxy-4a-methyl-1-(S)-methyl-1,2,3,4,...)
Affinity DataIC50:  270nMAssay Description:Inhibitory concentration in LXRSPA alpha binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50172190((4S,4aR)-6-Hydroxy-4a-methyl-1-(S)-methyl-1,2,3,4,...)
Affinity DataIC50:  200nMAssay Description:Inhibitory concentration in LXRSPA beta binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed