BDBM50172786 CHEMBL3809909

SMILES CC1(C)COC(=O)Nc2cccc(CNC(=O)[C@H](Nc3ccc4c(N)nccc4c3)c3ccc1cc3)c2

InChI Key InChIKey=BKXPNWHCZUBYGK-RUZDIDTESA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50172786   

TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50172786(CHEMBL3809909)
Affinity DataKi:  1.40nMAssay Description:Inhibition of recombinant human Tissue factor/factor 7a using S2288 as substrate after 30 to 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-1(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50172786(CHEMBL3809909)
Affinity DataKi:  25nMAssay Description:Inhibition of purified human tissue kallikrein 1 using H-D-Val-Leu-Arg-AFC as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypsin(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50172786(CHEMBL3809909)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of purified human trypsin after 30 to 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50172786(CHEMBL3809909)
Affinity DataKi: >1.15E+4nMAssay Description:Inhibition of purified human thrombin after 30 to 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50172786(CHEMBL3809909)
Affinity DataKi: >1.33E+4nMAssay Description:Inhibition of purified human factor 10a using S2765 as substrate after 30 to 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50172786(CHEMBL3809909)
Affinity DataKi: >1.42E+4nMAssay Description:Inhibition of purified human factor 11a after 30 to 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed