BDBM50173977 (2S,4S)-1-((R)-2-amino-3-(3-(4-fluorophenyl)propylthio)-3-methylbutanoyl)-4-fluoropyrrolidine-2-carbonitrile::CHEMBL199502

SMILES CC(C)(SCCCc1ccc(F)cc1)[C@H](N)C(=O)N1C[C@@H](F)C[C@H]1C#N

InChI Key InChIKey=IIKCZGQEACUCTC-YESZJQIVSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50173977   

TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50173977((2S,4S)-1-((R)-2-amino-3-(3-(4-fluorophenyl)propyl...)
Affinity DataKi:  45nMAssay Description:Inhibitory activity against human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50173977((2S,4S)-1-((R)-2-amino-3-(3-(4-fluorophenyl)propyl...)
Affinity DataKi:  701nMAssay Description:Inhibitory activity against recombinant DPP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl endopeptidase FAP(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50173977((2S,4S)-1-((R)-2-amino-3-(3-(4-fluorophenyl)propyl...)
Affinity DataKi:  1.58E+4nMAssay Description:Inhibitory activity against recombinant sepraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed