BDBM50174834 CHEMBL382280::N-(3-(3-(4-hydroxyphenyl)acryloyl)phenyl)-4-methylbenzenesulfonamide::Sulfonamide chalcone, 6

SMILES Cc1ccc(cc1)S(=O)(=O)Nc1cccc(c1)C(=O)\C=C\c1ccc(O)cc1

InChI Key InChIKey=ZSMBKKLWWRPLBX-NTEUORMPSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50174834   

TargetTrans-sialidase(Trypanosoma cruzi)
University Of British Columbia

LigandPNGBDBM50174834(CHEMBL382280 | N-(3-(3-(4-hydroxyphenyl)acryloyl)p...)
Affinity DataIC50:  3.70E+4nMpH: 7.6 T: 2°CAssay Description:Inhibition assay using trans-sialidase, a membrane-associated protein.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-amylase(Hordeum vulgare)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50174834(CHEMBL382280 | N-(3-(3-(4-hydroxyphenyl)acryloyl)p...)
Affinity DataIC50:  2.01E+5nMAssay Description:Inhibitory activity against barley beta amylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-mannosidase(Canavalia ensiformis)
Shiv Nadar University

Curated by ChEMBL
LigandPNGBDBM50174834(CHEMBL382280 | N-(3-(3-(4-hydroxyphenyl)acryloyl)p...)
Affinity DataIC50:  1.05E+5nMAssay Description:Inhibition of jack bean alpha-mannosidase using PNPG as substrate incubated for 10 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue alpha-L-fucosidase(Bos taurus)
Shiv Nadar University

Curated by ChEMBL
LigandPNGBDBM50174834(CHEMBL382280 | N-(3-(3-(4-hydroxyphenyl)acryloyl)p...)
Affinity DataIC50:  9.10E+4nMAssay Description:Inhibition of bovine kidney alpha-fucosidase using PNPG as substrate incubated for 10 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-amylase(Bacillus licheniformis)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50174834(CHEMBL382280 | N-(3-(3-(4-hydroxyphenyl)acryloyl)p...)
Affinity DataIC50:  3.73E+4nMAssay Description:Inhibitory activity against Bacillus licheniformis alpha amylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed