BDBM50178329 (3S,10S,13S,17S)-17-ethynyl-13-methyl-10-vinyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,17-diol::CHEMBL381566

SMILES C[C@]12CCC3C(CC=C4C[C@@H](O)CC[C@]34C=C)C1CC[C@@]2(O)C#C

InChI Key InChIKey=XEWBKAVLKISZRR-ALTMMPCJSA-N

Data  3 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50178329   

TargetEstrogen receptor beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50178329((3S,10S,13S,17S)-17-ethynyl-13-methyl-10-vinyl-2,3...)
Affinity DataIC50:  14nMAssay Description:Binding affinity to human ERbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50178329((3S,10S,13S,17S)-17-ethynyl-13-methyl-10-vinyl-2,3...)
Affinity DataEC50:  10nMAssay Description:Effect on transactivation of ALP gene expression in HEK293 cells transfected with hERalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50178329((3S,10S,13S,17S)-17-ethynyl-13-methyl-10-vinyl-2,3...)
Affinity DataIC50:  287nMAssay Description:Inhibitory activity against ARMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50178329((3S,10S,13S,17S)-17-ethynyl-13-methyl-10-vinyl-2,3...)
Affinity DataIC50:  147nMAssay Description:Binding affinity to human ERalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50178329((3S,10S,13S,17S)-17-ethynyl-13-methyl-10-vinyl-2,3...)
Affinity DataEC50:  24nMAssay Description:Effect on transactivation of ALP gene expression in HEK293 cells transfected with hERbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed