BDBM50178617 3-fluoro-N-(4-methyl-3-(4-(pyridin-3-yl)pyrimidin-2-ylamino)phenyl)-4-((4-methylpiperazin-1-yl)methyl)benzamide::CHEMBL205409

SMILES CN1CCN(Cc2ccc(cc2F)C(=O)Nc2ccc(C)c(Nc3nccc(n3)-c3cccnc3)c2)CC1

InChI Key InChIKey=YZLKFFPFWYDBEB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50178617   

TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
Nippon Shinyaku

Curated by ChEMBL
LigandPNGBDBM50178617(3-fluoro-N-(4-methyl-3-(4-(pyridin-3-yl)pyrimidin-...)
Affinity DataIC50:  35nMAssay Description:Inhibition of human Lyn kinase expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
The First People'S Hospital Of Hangzhou

Curated by ChEMBL
LigandPNGBDBM50178617(3-fluoro-N-(4-methyl-3-(4-(pyridin-3-yl)pyrimidin-...)
Affinity DataIC50:  63nMAssay Description:Inhibition of BCR-ABL kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Nippon Shinyaku

Curated by ChEMBL
LigandPNGBDBM50178617(3-fluoro-N-(4-methyl-3-(4-(pyridin-3-yl)pyrimidin-...)
Affinity DataIC50:  120nMAssay Description:Inhibition of human Abl kinase expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed