BDBM50179250 CHEMBL3813826
SMILES OC(=O)C1=NN(C(=O)\C1=C/c1ccc(cc1)N(CCC#N)CCC#N)c1ccc(cc1)S(O)(=O)=O
InChI Key InChIKey=USLVVQDIRKDBSF-HKWRFOASSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50179250
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Georgia State University
Curated by ChEMBL
Georgia State University
Curated by ChEMBL
Affinity DataIC50: >1.11E+5nMAssay Description:Inhibition of human recombinant TDP1 using 5'-[32P]-labeled N14Y as substrate after 15 mins by PAGE methodMore data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Georgia State University
Curated by ChEMBL
Georgia State University
Curated by ChEMBL
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of human recombinant TDP2 using alpha32P-cordycepin-3'-labeled TY19 as substrate after 15 mins by PAGE methodMore data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Mus musculus (Mouse))
Georgia State University
Curated by ChEMBL
Georgia State University
Curated by ChEMBL
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of mouse recombinant TDP2 using alpha32P-cordycepin-3'-labeled TY19 as substrate after 15 mins by PAGE methodMore data for this Ligand-Target Pair
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of zebra fish recombinant TDP2 using alpha32P-cordycepin-3'-labeled TY19 as substrate after 15 mins by PAGE methodMore data for this Ligand-Target Pair