BDBM50179250 CHEMBL3813826

SMILES OC(=O)C1=NN(C(=O)\C1=C/c1ccc(cc1)N(CCC#N)CCC#N)c1ccc(cc1)S(O)(=O)=O

InChI Key InChIKey=USLVVQDIRKDBSF-HKWRFOASSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50179250   

TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50179250(CHEMBL3813826)
Affinity DataIC50: >1.11E+5nMAssay Description:Inhibition of human recombinant TDP1 using 5'-[32P]-labeled N14Y as substrate after 15 mins by PAGE methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50179250(CHEMBL3813826)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of human recombinant TDP2 using alpha32P-cordycepin-3'-labeled TY19 as substrate after 15 mins by PAGE methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 2(Mus musculus (Mouse))
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50179250(CHEMBL3813826)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of mouse recombinant TDP2 using alpha32P-cordycepin-3'-labeled TY19 as substrate after 15 mins by PAGE methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 2(Danio rerio)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50179250(CHEMBL3813826)
Affinity DataIC50:  5.20E+3nMAssay Description:Inhibition of zebra fish recombinant TDP2 using alpha32P-cordycepin-3'-labeled TY19 as substrate after 15 mins by PAGE methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed