BDBM50180257 1-(2-aminoethyl)-1H-indazol-6-ol::CHEMBL199385

SMILES NCCn1ncc2ccc(O)cc12

InChI Key InChIKey=RVQKKYXTHSVLLB-UHFFFAOYSA-N

Data  3 KI  1 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50180257   

Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Alcon Research

Curated by ChEMBL
LigandPNGBDBM50180257(1-(2-aminoethyl)-1H-indazol-6-ol | CHEMBL199385)
Affinity DataKi:  9.60nMAssay Description:Displacement of [125I]DOI from cloned human 5HT2C receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Alcon Research

Curated by ChEMBL
LigandPNGBDBM50180257(1-(2-aminoethyl)-1H-indazol-6-ol | CHEMBL199385)
Affinity DataKi:  15nMAssay Description:Displacement of [125I]DOI from cloned human 5HT2B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Alcon Research

Curated by ChEMBL
LigandPNGBDBM50180257(1-(2-aminoethyl)-1H-indazol-6-ol | CHEMBL199385)
Affinity DataKi:  20nMAssay Description:Displacement of [125I]DOI from cloned human 5HT2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Alcon Research

Curated by ChEMBL
LigandPNGBDBM50180257(1-(2-aminoethyl)-1H-indazol-6-ol | CHEMBL199385)
Affinity DataEC50:  74nMAssay Description:Activity against 5HT2A mediated intracellular calcium mobilization by FLIPR in rat vascular smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(RAT)
Alcon Research

Curated by ChEMBL
LigandPNGBDBM50180257(1-(2-aminoethyl)-1H-indazol-6-ol | CHEMBL199385)
Affinity DataEC50:  8.60nMAssay Description:Activity against 5HT2B receptor in longitudinal stomach fundus strips in wistar ratsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Alcon Research

Curated by ChEMBL
LigandPNGBDBM50180257(1-(2-aminoethyl)-1H-indazol-6-ol | CHEMBL199385)
Affinity DataIC50:  0.770nMAssay Description:Inhibition of [125I]DOI binding to 5HT2A receptor in rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Alcon Research

Curated by ChEMBL
LigandPNGBDBM50180257(1-(2-aminoethyl)-1H-indazol-6-ol | CHEMBL199385)
Affinity DataEC50:  4.5nMAssay Description:Activity against recombinant rat 5HT2C mediated intracellular calcium mobilization by FLIPR in SR3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed