BDBM50180995 (S)-4-(4-(4-aminobut-2-ynyloxy)phenylsulfonyl)-N-hydroxy-2,2-dimethylthiomorpholine-3-carboxamide::4-({4-[(4-AMINOBUT-2-YNYL)OXY]PHENYL}SULFONYL)-N-HYDROXY-2,2-DIMETHYLTHIOMORPHOLINE-3-CARBOXAMIDE::CHEMBL202839

SMILES CC1(C)SCCN([C@H]1C(=O)NO)S(=O)(=O)c1ccc(OCC#CCN)cc1

InChI Key InChIKey=AANXPIMDONQTQF-HNNXBMFYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50180995   

TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50180995((S)-4-(4-(4-aminobut-2-ynyloxy)phenylsulfonyl)-N-h...)
Affinity DataIC50:  8nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50180995((S)-4-(4-(4-aminobut-2-ynyloxy)phenylsulfonyl)-N-h...)
Affinity DataIC50:  97nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50180995((S)-4-(4-(4-aminobut-2-ynyloxy)phenylsulfonyl)-N-h...)
Affinity DataIC50:  67nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair