BDBM50181154 1-(3,4-dichlorophenyl)-3-(N-hydroxyformamido)propylphosphonic acid::CHEMBL204106::ammonium 1-(3,4-dichlorophenyl)-3-(N-hydroxyformamido)propylphosphonate

SMILES ON(CCC(c1ccc(Cl)c(Cl)c1)P(O)(O)=O)C=O

InChI Key InChIKey=AJGPMMOCRYQLNY-UHFFFAOYSA-N

Data  1 KI  2 IC50  1 Kd

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50181154   

Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium tuberculosis)
Baylor College Of Medicine

Curated by ChEMBL
LigandPNGBDBM50181154(1-(3,4-dichlorophenyl)-3-(N-hydroxyformamido)propy...)
Affinity DataKi:  1.20E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant DXR expressed in Escherichia coli BL21 (DE3) using DXP as substrate and MgCl2 as cofactor preinc...More data for this Ligand-Target Pair
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli)
Baylor College Of Medicine

Curated by ChEMBL
LigandPNGBDBM50181154(1-(3,4-dichlorophenyl)-3-(N-hydroxyformamido)propy...)
Affinity DataIC50:  59nMAssay Description:Inhibition of Escherichia coli DXRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium tuberculosis)
Baylor College Of Medicine

Curated by ChEMBL
LigandPNGBDBM50181154(1-(3,4-dichlorophenyl)-3-(N-hydroxyformamido)propy...)
Affinity DataKd:  120nMAssay Description:Binding affinity to Mycobacterium tuberculosis DXR assessed as dissociation constant by spectrofluorimetric analysis in presence of NADPH and MnCl2More data for this Ligand-Target Pair
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli)
Baylor College Of Medicine

Curated by ChEMBL
LigandPNGBDBM50181154(1-(3,4-dichlorophenyl)-3-(N-hydroxyformamido)propy...)
Affinity DataIC50:  59nMAssay Description:Inhibition of recombinant Escherichia coli DXRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed