BDBM50182816 2-(pyridin-2-yl)-4-(3-(trifluoromethyl)phenylthio)pyrimidine::CHEMBL204950

SMILES FC(F)(F)c1cccc(Sc2ccnc(n2)-c2ccccn2)c1

InChI Key InChIKey=QDQLHDJCSXWHHL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50182816   

TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50182816(2-(pyridin-2-yl)-4-(3-(trifluoromethyl)phenylthio)...)
Affinity DataIC50:  550nMAssay Description:Inhibition of glutamate-induced calcium influx in human mGluR5d by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed