BDBM50183273 (S)-6-(3-chloro-2-fluorobenzyl)-1-(1-hydroxy-3-methylbutan-2-yl)-7-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid::6-(3-Chloro-2-fluorobenzyl)-1-((2S)-1-hydroxy-3-methylbutan-2-yl)-7-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid::6-(3-chloro-2-fluorobenzyl)-1-[(1S)-1-(hydroxymethyl)-2-methylpropyl]-7-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid::CHEMBL204656::ELVITEGRAVIR
SMILES COc1cc2n(cc(C(O)=O)c(=O)c2cc1Cc1cccc(Cl)c1F)[C@H](CO)C(C)C
InChI Key InChIKey=JUZYLCPPVHEVSV-LJQANCHMSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 29 hits for monomerid = 50183273
Affinity DataIC50: 28nMAssay Description:Inhibition of HIV1 integrase strand transfer activity by gel-based assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1nMAssay Description:Inhibition of HIV-1 integrase mutant strand transfer activity incubated for 10 mins by enzymatic assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.20nMAssay Description:Inhibition of recombinant HIV1 integrase strand transfer activityMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of HIV-1 integrase assessed as inhibition of strand transfer activity using 32P-labeled DNA as substrate after 1 hr by gel-based assay in ...More data for this Ligand-Target Pair
Affinity DataIC50: 9.10E+4nMAssay Description:Inhibition of RNase H function of HIV1 reverse transcriptase using DNA/RNA hybrid as substrate by fluorescence spectrometer analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibition of HIV-1 integrase assessed as inhibition of 3'-processing activity using 32P-labeled DNA as substrate after 1 hr by gel-based assay in pr...More data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Inhibition of HIV1 integraseMore data for this Ligand-Target Pair
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of HIV1 integrase strand transfer activityMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of HIV-1 integrase after 1 hr by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 3.80nMAssay Description:Inhibition of Human immunodeficiency virus 1 integraseMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of Human immunodeficiency virus 1 integrase strand transfer activityMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of HIV1 integrase 3'-processing activityMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of HIV1 integrase by overall integration assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of HIV1 integrase DNA strand transfer activityMore data for this Ligand-Target Pair
Affinity DataIC50: 7.20nMAssay Description:Inhibition of HIV-1 integraseMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of strand transfer activity of Human immunodeficiency virus 1 Integrase using [3H]labeled target DNA as substrate after 45 mins by scintil...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of HIV1 integrase strand transferMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of HIV1 integraseMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of HIV1 integrase 3'-end processing activityMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of HIV1 integrase strand transfer activityMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of HIV1 integraseMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Displacement of 20 nM [3H]GSK304649 from Human immunodeficiency virus 1 integrase by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of Human immunodeficiency virus 1 integrase by strand transfer scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of HIV1 integraseMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of HIV1 integrase strand transfer activityMore data for this Ligand-Target Pair
Affinity DataIC50: 7.20nMAssay Description:Inhibition of HIV1 integrase strand transfer activityMore data for this Ligand-Target Pair
Affinity DataIC50: 3.80nMAssay Description:Inhibition of HIV integrase strand transfer activityMore data for this Ligand-Target Pair
Affinity DataEC50: 0.210nMAssay Description:Inhibition of HIV-1 integrase strand transfer activity incubated for 10 mins by enzymatic assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibition of HIV1 integrase 3'-processing activity by gel-based assaysMore data for this Ligand-Target Pair