BDBM50184635 6-(2-fluorophenyl)-2,4,6-trioxohexanoic acid::CHEMBL209827

SMILES: OC(=O)C(=O)CC(=O)CC(=O)c1ccccc1F

InChI Key: InChIKey=ODTYWXMRFLCEFZ-UHFFFAOYSA-N

Data: 1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50184635   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 integrase (Human immunodeficiency virus 1)	BDBM50184635 (6-(2-fluorophenyl)-2,4,6-trioxohexanoic acid | CHE...) Show SMILES OC(=O)C(=O)CC(=O)CC(=O)c1ccccc1F Show InChI InChI=1S/C12H9FO5/c13-9-4-2-1-3-8(9)10(15)5-7(14)6-11(16)12(17)18/h1-4H,5-6H2,(H,17,18)	PDB MMDB UniProtKB/TrEMBL DrugBank GoogleScholar	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Co. Curated by ChEMBL					Assay Description Inhibition of HIV1 recombinant integrase				Bioorg Med Chem Lett 16: 2920-4 (2006) Article DOI: 10.1016/j.bmcl.2006.03.010 BindingDB Entry DOI: 10.7270/Q2BV7HDK
					More data for this Ligand-Target Pair