BDBM50191514 2-{4-[2-(4-chlorophenyl)pyridin-3-ylmethoxy]phenyl}-1-cyclohexyl-1H-benzimidazole-5-carboxylic acid::CHEMBL212582

SMILES OC(=O)c1ccc2n(C3CCCCC3)c(nc2c1)-c1ccc(OCc2cccnc2-c2ccc(Cl)cc2)cc1

InChI Key InChIKey=WCRPMXRVEWRLMT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50191514   

TargetRNA-directed RNA polymerase(Hepatitis C virus)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50191514(2-{4-[2-(4-chlorophenyl)pyridin-3-ylmethoxy]phenyl...)
Affinity DataIC50:  53nMAssay Description:Inhibition of HCV 1b BK six His-tagged C-terminal truncated 544 amino acid NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1)TBA
LigandPNGBDBM50191514(2-{4-[2-(4-chlorophenyl)pyridin-3-ylmethoxy]phenyl...)
Affinity DataIC50:  1.88E+7nMAssay Description:Inhibition of Hepatitis C virus genotype 1 NS5B polymerases lacking C-terminal 47 amino acid residues expressed in Escherichia coli after 60 minMore data for this Ligand-Target Pair
In DepthDetails Article
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1)TBA
LigandPNGBDBM50191514(2-{4-[2-(4-chlorophenyl)pyridin-3-ylmethoxy]phenyl...)
Affinity DataIC50:  1.89E+7nMAssay Description:Inhibition of Hepatitis C virus genotype 1 NS5B polymerases lacking C-terminal 47 amino acid residues expressed in Escherichia coli after 60 minMore data for this Ligand-Target Pair
In DepthDetails Article