BDBM50191520 2-[4-(biphenyl-2-ylmethoxy)-2-methoxyphenyl]-1-cyclohexyl-1H-benzoimidazole-5-carboxylic acid::CHEMBL212226

SMILES COc1cc(OCc2ccccc2-c2ccccc2)ccc1-c1nc2cc(ccc2n1C1CCCCC1)C(O)=O

InChI Key InChIKey=ZVULSSSMANUZDD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50191520   

TargetRNA-directed RNA polymerase(Hepatitis C virus)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50191520(2-[4-(biphenyl-2-ylmethoxy)-2-methoxyphenyl]-1-cyc...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of HCV 1b BK six His-tagged C-terminal truncated 544 amino acid NS5B RNA dependent RNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1)TBA
LigandPNGBDBM50191520(2-[4-(biphenyl-2-ylmethoxy)-2-methoxyphenyl]-1-cyc...)
Affinity DataIC50:  9.10E+5nMAssay Description:Inhibition of Hepatitis C virus genotype 1 NS5B polymerases lacking C-terminal 47 amino acid residues expressed in Escherichia coli after 60 minMore data for this Ligand-Target Pair
In DepthDetails Article
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1)TBA
LigandPNGBDBM50191520(2-[4-(biphenyl-2-ylmethoxy)-2-methoxyphenyl]-1-cyc...)
Affinity DataIC50:  9.09E+5nMAssay Description:Inhibition of Hepatitis C virus genotype 1 NS5B polymerases lacking C-terminal 47 amino acid residues expressed in Escherichia coli after 60 minMore data for this Ligand-Target Pair
In DepthDetails Article