BDBM50195153 (8S,11R,13S,14S,17S)-17-hydroxy-11-(4-methoxy-phenyl)-13-methyl-17-prop-1-ynyl-1,2,6,7,8,11,12,13,14,15,16,17-dodecahydro-cyclopenta[a]phenanthren-3-one::17beta-Hydroxy-11beta-[4-methoxyphenyl]-17alpha-(1-propinyl)-estra-4,9-dien-3-one::CHEMBL221686

SMILES COc1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@@]2(O)C#CC)[C@@H]2CCC3=CC(=O)CCC3=C12

InChI Key InChIKey=OAYLSAHITBROEB-WKWWZUSTSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50195153   

TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195153((8S,11R,13S,14S,17S)-17-hydroxy-11-(4-methoxy-phen...)
Affinity DataIC50:  0.900nMAssay Description:Binding affinity to human GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
University Of Graz

Curated by ChEMBL
LigandPNGBDBM50195153((8S,11R,13S,14S,17S)-17-hydroxy-11-(4-methoxy-phen...)
Affinity DataIC50:  0.0950nMAssay Description:Antagonist activity at progesterone receptor in human T47D cells assessed as inhibition of progesterone-induced alkaline phosphatase activity after 4...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195153((8S,11R,13S,14S,17S)-17-hydroxy-11-(4-methoxy-phen...)
Affinity DataIC50:  7.60nMAssay Description:Activity at GR expressed in CHO cells assessed as decrease in dexamethasone-stimulated alkaline phosphatase production by GRAF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed