BDBM50195500 (4-amino-3,5-dichlorophenyl)(4-(5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)methanone::CHEMBL223424

SMILES Nc1c(Cl)cc(cc1Cl)C(=O)N1CCN(CC1)c1ccc(cn1)C(F)(F)F

InChI Key InChIKey=RPLUJXKPOYQZGI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50195500   

Target11-beta-hydroxysteroid dehydrogenase type 2(Rattus norvegicus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195500((4-amino-3,5-dichlorophenyl)(4-(5-(trifluoromethyl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of rat 11beta-HSD2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195500((4-amino-3,5-dichlorophenyl)(4-(5-(trifluoromethyl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human 11beta-HSD1 expressed in Escherichia coli by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50195500((4-amino-3,5-dichlorophenyl)(4-(5-(trifluoromethyl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human 11beta-HSD2 by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed