BDBM50197405 2-(4-chloro-phenoxy)-N-(5-methanesulfonyl-adamantan-2-yl)-2-methyl-propionamide::CHEMBL241716

SMILES CC(C)(Oc1ccc(Cl)cc1)C(=O)N[C@H]1C2CC3CC1C[C@](C3)(C2)S(C)(=O)=O

InChI Key InChIKey=RSHUECPBXOMFTQ-YLGPJNIESA-N

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50197405   

Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197405(2-(4-chloro-phenoxy)-N-(5-methanesulfonyl-adamanta...)
Affinity DataKi:  7nMAssay Description:Inhibition of human HSD1 assessed as interconversion of cortisone to cortisolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197405(2-(4-chloro-phenoxy)-N-(5-methanesulfonyl-adamanta...)
Affinity DataKi:  8nMAssay Description:Inhibition of mouse HSD1 assessed as interconversion of cortisone to cortisolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197405(2-(4-chloro-phenoxy)-N-(5-methanesulfonyl-adamanta...)
Affinity DataIC50:  6.50E+4nMAssay Description:Inhibition of human HSD2 assessed as interconversion of cortisone to cortisolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Mus musculus (mouse))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197405(2-(4-chloro-phenoxy)-N-(5-methanesulfonyl-adamanta...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of mouse HSD2 assessed as interconversion of cortisone to cortisolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50197405(2-(4-chloro-phenoxy)-N-(5-methanesulfonyl-adamanta...)
Affinity DataIC50:  410nMAssay Description:Inhibition of human HSD1 expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed