BDBM50199901 3-((1R,2R,7R,9-alpha-R)-1,2-dimethyl-7-phenyl-octahydro-1H-quinolizin-2-yl)phenol::CHEMBL385280

SMILES C[C@H]1[C@H]2CC[C@@H](CN2CC[C@@]1(C)c1cccc(O)c1)c1ccccc1

InChI Key InChIKey=RBPDWVPVDMDPMQ-KMGZYFLFSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50199901   

TargetDelta-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50199901(3-((1R,2R,7R,9-alpha-R)-1,2-dimethyl-7-phenyl-octa...)
Affinity DataKi:  25nMAssay Description:Displacement of [3H]diprenorphine from human cloned delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50199901(3-((1R,2R,7R,9-alpha-R)-1,2-dimethyl-7-phenyl-octa...)
Affinity DataKi:  26nMAssay Description:Antagonist activity against human cloned mu opioid receptor expressed in CHO cells assessed as inhibition of loperamide-stimulated [35S]GTP-gamma-S b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50199901(3-((1R,2R,7R,9-alpha-R)-1,2-dimethyl-7-phenyl-octa...)
Affinity DataKi:  35nMAssay Description:Partial agonist activity at human cloned kappa opioid receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50199901(3-((1R,2R,7R,9-alpha-R)-1,2-dimethyl-7-phenyl-octa...)
Affinity DataIC50:  190nMAssay Description:Antagonist activity against human cloned mu opioid receptor expressed in CHO cells assessed as inhibition of loperamide-stimulated [35S]GTP-gamma-S b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed