BDBM50199905 3-((2R,3R,7R,9-alpha-R)-2,3-dimethyl-7-phenyl-octahydro-1H-quinolizin-2-yl)phenol::CHEMBL219079

SMILES C[C@H]1CN2C[C@H](CC[C@@H]2C[C@@]1(C)c1cccc(O)c1)c1ccccc1

InChI Key InChIKey=RGXBTFPNFYCKOY-VARILPKDSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50199905   

TargetMu-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50199905(3-((2R,3R,7R,9-alpha-R)-2,3-dimethyl-7-phenyl-octa...)
Affinity DataKi:  430nMAssay Description:Antagonist activity against human cloned mu opioid receptor expressed in CHO cells assessed as inhibition of loperamide-stimulated [35S]GTP-gamma-S b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL
LigandPNGBDBM50199905(3-((2R,3R,7R,9-alpha-R)-2,3-dimethyl-7-phenyl-octa...)
Affinity DataKi:  1.40E+3nMAssay Description:Partial agonist activity at human cloned kappa opioid receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed