BDBM50200981 CHEMBL3960148::US10138212, Example 6

SMILES COc1cccc2c(nc(N)nc12)C(=O)NCc1cccc(n1)C1CCC1

InChI Key InChIKey=GJNGFJWIAZMTNC-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50200981   

TargetAdenosine receptor A2a(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50200981(CHEMBL3960148 | US10138212, Example 6)
Affinity DataKi:  0.200nMAssay Description:Binding affinities of compounds of the invention for the human A2a receptor were determined in a competition binding assay using Scintillation Proxim...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenosine receptor A2a(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50200981(CHEMBL3960148 | US10138212, Example 6)
Affinity DataKi:  0.200nMAssay Description:Displacement of [3H]5-amino-7-[2- phenethyl]-2-(furan-2-yl)-7H-pyrazolo[4,3-e][l,2,4]triazolo[l,5-c]pyrimidine from human adenosine A2A receptor expr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed