BDBM50201698 CHEMBL230473::rac-trans4-(2,3-dimethylphenoxy)-6-oxa-1-aza-bicyclo[3.2.1]octan-7-one

SMILES Cc1cccc(O[C@H]2CCN3C[C@@H]2OC3=O)c1C

InChI Key InChIKey=SIIJWJNEODXHNY-STQMWFEESA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50201698   

TargetDipeptidyl peptidase 1(Homo sapiens (Human))
The Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50201698(CHEMBL230473 | rac-trans4-(2,3-dimethylphenoxy)-6-...)
Affinity DataIC50:  1.73E+3nMAssay Description:Inhibition of human recombinant cathepsin CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPro-cathepsin H(Homo sapiens (Human))
The Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50201698(CHEMBL230473 | rac-trans4-(2,3-dimethylphenoxy)-6-...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human recombinant cathepsin HMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
The Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50201698(CHEMBL230473 | rac-trans4-(2,3-dimethylphenoxy)-6-...)
Affinity DataIC50:  553nMAssay Description:Inhibition of human recombinant cathepsin XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
The Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50201698(CHEMBL230473 | rac-trans4-(2,3-dimethylphenoxy)-6-...)
Affinity DataIC50:  473nMAssay Description:Inhibition of human recombinant cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin L2(Homo sapiens (Human))
The Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50201698(CHEMBL230473 | rac-trans4-(2,3-dimethylphenoxy)-6-...)
Affinity DataIC50:  3.32E+3nMAssay Description:Inhibition of human recombinant cathepsin VMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
The Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50201698(CHEMBL230473 | rac-trans4-(2,3-dimethylphenoxy)-6-...)
Affinity DataIC50:  46nMAssay Description:Inhibition of human recombinant cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
The Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50201698(CHEMBL230473 | rac-trans4-(2,3-dimethylphenoxy)-6-...)
Affinity DataIC50:  1.27E+3nMAssay Description:Inhibition of human recombinant cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin F(Homo sapiens (Human))
The Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50201698(CHEMBL230473 | rac-trans4-(2,3-dimethylphenoxy)-6-...)
Affinity DataIC50:  5.91E+3nMAssay Description:Inhibition of human recombinant cathepsin FMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
The Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50201698(CHEMBL230473 | rac-trans4-(2,3-dimethylphenoxy)-6-...)
Affinity DataIC50:  2.44E+3nMAssay Description:Inhibition of human recombinant cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed