BDBM50203333 CHEMBL3968178
SMILES FC(F)S(=O)(=O)N1CCN(CC1)c1ccc(OC[C@@H]2CO[C@](Cn3ccnc3)(O2)c2ccc(Cl)cc2Cl)cc1
InChI Key InChIKey=NRJZYAWVYYNCON-PXDATVDWSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50203333
TargetCytochrome P450 3A4(Homo sapiens (Human))
Temple University School Of Pharmacy
Curated by ChEMBL
Temple University School Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 99nMAssay Description:Inhibition of human Cyp3A4 using testosterone as substrate by LC-MS/MS analysisMore data for this Ligand-Target Pair
TargetSteroid 21-hydroxylase(Homo sapiens (Human))
Temple University School Of Pharmacy
Curated by ChEMBL
Temple University School Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of recombinant CYP21 (unknown origin) overexpressed in human AD293 cells assessed as reduction in 11-deoxycortisol formation preincubated ...More data for this Ligand-Target Pair
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Temple University School Of Pharmacy
Curated by ChEMBL
Temple University School Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of recombinant CYP11B1 (unknown origin) overexpressed in human AD293 cells assessed as reduction in cortisol formation preincubated for 60...More data for this Ligand-Target Pair
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Temple University School Of Pharmacy
Curated by ChEMBL
Temple University School Of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant CYP17 (unknown origin) overexpressed in human AD293 cells using [21-3H]17alpha-hydroxyl-pregenolone as substrate preincubat...More data for this Ligand-Target Pair
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of Cyp19 (unknown origin)More data for this Ligand-Target Pair