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BDBM50203376 CHEMBL234826::naphthalene-2-carboxylic acid [1-(4-methyl-benzyl)-piperidin-4-yl]-amide

SMILES: Cc1ccc(CN2CCC(CC2)NC(=O)c2ccc3ccccc3c2)cc1

InChI Key: InChIKey=RBTINXLOMJSVQS-UHFFFAOYSA-N

Data: 2 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50203376   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
D(4) dopamine receptor


(Homo sapiens (Human))
BDBM50203376
PNG
(CHEMBL234826 | naphthalene-2-carboxylic acid [1-(4...)
Show SMILES Cc1ccc(CN2CCC(CC2)NC(=O)c2ccc3ccccc3c2)cc1
Show InChI InChI=1S/C24H26N2O/c1-18-6-8-19(9-7-18)17-26-14-12-23(13-15-26)25-24(27)22-11-10-20-4-2-3-5-21(20)16-22/h2-11,16,23H,12-15,17H2,1H3,(H,25,27)
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KEGG

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
21n/an/an/an/an/an/an/an/a



Université du Droit et de la Santé Lille II

Curated by ChEMBL


Assay Description
Displacement of [3H]nemonapride from human cloned dopamine D4.2 receptor


Bioorg Med Chem Lett 17: 1570-4 (2007)


Article DOI: 10.1016/j.bmcl.2006.12.106
BindingDB Entry DOI: 10.7270/Q2Z037T3
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Rattus norvegicus (rat))
BDBM50203376
PNG
(CHEMBL234826 | naphthalene-2-carboxylic acid [1-(4...)
Show SMILES Cc1ccc(CN2CCC(CC2)NC(=O)c2ccc3ccccc3c2)cc1
Show InChI InChI=1S/C24H26N2O/c1-18-6-8-19(9-7-18)17-26-14-12-23(13-15-26)25-24(27)22-11-10-20-4-2-3-5-21(20)16-22/h2-11,16,23H,12-15,17H2,1H3,(H,25,27)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
222n/an/an/an/an/an/an/an/a



Université du Droit et de la Santé Lille II

Curated by ChEMBL


Assay Description
Displacement of [3H]ketanserin from rat 5HT2A receptor


Bioorg Med Chem Lett 17: 1570-4 (2007)


Article DOI: 10.1016/j.bmcl.2006.12.106
BindingDB Entry DOI: 10.7270/Q2Z037T3
More data for this
Ligand-Target Pair