BDBM50206061 CHEMBL3953102::US10336721, Example 1::US10968198, Example 1
SMILES Oc1ccc(cc1)-n1cc(nn1)-c1ccc2ccccc2n1
InChI Key InChIKey=QSDNOMVFORBNKO-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50206061
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Indian Institute Of Technology (B.H.U.)
Curated by ChEMBL
Indian Institute Of Technology (B.H.U.)
Curated by ChEMBL
Affinity DataKi: 230nMAssay Description:Inhibition of recombinant human MIF tautomerase activity using 4-hydroxyphenyl pyruvic acid (HPP) as substrate pre-incubated for 30 mins and followed...More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Indian Institute Of Technology (B.H.U.)
Curated by ChEMBL
Indian Institute Of Technology (B.H.U.)
Curated by ChEMBL
Affinity DataKi: 230nMAssay Description:Inhibition of recombinant human MIF tautomerase activity expressed in Escherichia coli assessed as borate-enol complex formation using 4-hydroxypheny...More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Indian Institute Of Technology (B.H.U.)
Curated by ChEMBL
Indian Institute Of Technology (B.H.U.)
Curated by ChEMBL
Affinity DataKi: 230nMAssay Description:Inhibition of recombinant human MIF tautomerase activity expressed in Escherichia coli assessed as decrease in formation of borate complex of enol pr...More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Indian Institute Of Technology (B.H.U.)
Curated by ChEMBL
Indian Institute Of Technology (B.H.U.)
Curated by ChEMBL
Affinity DataKi: 440nMAssay Description:Inhibition of C-terminal His-tagged recombinant human MIF tautomerase activity expressed in Escherichia coli BL21 using 4-hydroxyphenyl pyruvic acid ...More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Indian Institute Of Technology (B.H.U.)
Curated by ChEMBL
Indian Institute Of Technology (B.H.U.)
Curated by ChEMBL
Affinity DataKi: 590nMAssay Description:Inhibition of the tautomerase activity of MIF was measured using 4-hydroxyphenyl pyruvic acid (HPP) as substrate, largely following previously report...More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Indian Institute Of Technology (B.H.U.)
Curated by ChEMBL
Indian Institute Of Technology (B.H.U.)
Curated by ChEMBL
Affinity DataKi: 590nMAssay Description:Data obtained for the Example compounds, obtained using the methods described in Example B.More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Indian Institute Of Technology (B.H.U.)
Curated by ChEMBL
Indian Institute Of Technology (B.H.U.)
Curated by ChEMBL
Affinity DataKi: 590nMAssay Description:Inhibition of recombinant human MIF tautomerase activity expressed in Escherichia coli using 4-hydroxyphenyl pyruvic acid as substrate preincubated f...More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Indian Institute Of Technology (B.H.U.)
Curated by ChEMBL
Indian Institute Of Technology (B.H.U.)
Curated by ChEMBL
Affinity DataKd: 260nMAssay Description:Inhibition of recombinant human MIF tautomerase activity assessed as decrease in formation of borate complex of enol product using 4-HPP as substrate...More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Indian Institute Of Technology (B.H.U.)
Curated by ChEMBL
Indian Institute Of Technology (B.H.U.)
Curated by ChEMBL
Affinity DataIC50: 640nMAssay Description:Inhibition of C-terminal His-tagged recombinant human MIF tautomerase activity expressed in Escherichia coli BL21 using 4-hydroxyphenyl pyruvic acid ...More data for this Ligand-Target Pair