BDBM50210337 CHEMBL3970672

SMILES OCCc1cc(on1)-c1cncc(c1)N1CCCNCC1

InChI Key InChIKey=VQUBBGRWUMHAJX-UHFFFAOYSA-N

Data  6 KI  3 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50210337   

TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50210337(CHEMBL3970672)
Affinity DataKi:  0.800nMAssay Description:Displacement of [3H]epibatidine from rat alpha4beta2 nAChR by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-2/beta-2(Rattus norvegicus (Rat))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50210337(CHEMBL3970672)
Affinity DataKi:  0.800nMAssay Description:Displacement of [3H]epibatidine from rat alpha2beta2 nAChR by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Rattus norvegicus (Rat))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50210337(CHEMBL3970672)
Affinity DataKi:  42nMAssay Description:Displacement of [3H]epibatidine from rat alpha3beta2 nAChR by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-4(Rattus norvegicus (Rat))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50210337(CHEMBL3970672)
Affinity DataKi:  68nMAssay Description:Displacement of [3H]epibatidine from rat alpha4beta4 nAChR by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-2/beta-4(Rattus norvegicus (Rat))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50210337(CHEMBL3970672)
Affinity DataKi:  331nMAssay Description:Displacement of [3H]epibatidine from rat alpha2beta4 nAChR by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Rattus norvegicus (Rat))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50210337(CHEMBL3970672)
Affinity DataKi:  8.10E+3nMAssay Description:Displacement of [3H]epibatidine from rat alpha3beta4 nAChR by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50210337(CHEMBL3970672)
Affinity DataEC50:  31nMAssay Description:Agonist activity at human alpha4beta2 nAChR expressed in human SH-EP1 cells after 9.5 mins by 86Rb+ efflux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50210337(CHEMBL3970672)
Affinity DataEC50:  31nMAssay Description:Agonist activity at human alpha4beta2 nAChR expressed in human SH-EP1 cells after 9.5 mins by 86Rb+ efflux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50210337(CHEMBL3970672)
Affinity DataIC50:  51nMAssay Description:Antagonist activity at human alpha4beta2 expressed in human SH-EP1 cells assessed as reduction in carbamylcholine induced 86Rb+ efflux preincubated f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50210337(CHEMBL3970672)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at alpha1beta1gammadelta nAChR in human TE671/RD cells assessed as reduction in carbamylcholine induced 86Rb+ efflux preincubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50210337(CHEMBL3970672)
Affinity DataIC50:  51nMAssay Description:Antagonist activity at human alpha4beta2 expressed in human SH-EP1 cells assessed as reduction in carbamylcholine induced 86Rb+ efflux preincubated f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50210337(CHEMBL3970672)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at alpha1beta1gammadelta nAChR in human TE671/RD cells after 9.5 mins by 86Rb+ efflux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed