BDBM50211225 CHEMBL3957831

SMILES CN1CCN(Cc2ccc(cc2C(F)(F)F)C(=O)Nc2ccc(C)c(OC3CCN(CC3)C(=O)c3cncc(C)c3)c2)CC1

InChI Key InChIKey=MAEHWTXHQDRFIE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50211225   

TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
High Magnetic Field Laboratory

Curated by ChEMBL
LigandPNGBDBM50211225(CHEMBL3957831)
Affinity DataIC50:  6nMAssay Description:Inhibition of C-terminal His-tagged human ABL1 expressed in baculovirus infected SF9 cells using Tyr 02 peptide as substrate measured after 1 hr by F...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
High Magnetic Field Laboratory

Curated by ChEMBL
LigandPNGBDBM50211225(CHEMBL3957831)
Affinity DataIC50:  214nMAssay Description:Inhibition of recombinant C-terminal polyhistidine-tagged human c-KIT expressed in mammalian expression system using Tyr 06 peptide as substrate meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed