BDBM50211265 CHEMBL3954476

SMILES OC(c1cnn(n1)C(=O)N1CCCC[C@@H]1Cc1ccccc1)(c1ccc(F)cc1)c1ccc(F)cc1

InChI Key InChIKey=UEELPDUETDSIAP-RUZDIDTESA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50211265   

TargetDiacylglycerol lipase-alpha(Mus musculus)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50211265(CHEMBL3954476)
Affinity DataKi:  10nMAssay Description:Inhibition of mouse DAGL-alpha expressed in HEK293T cell membranes assessed as inhibition constant pre-incubated for 20 mins before PNP-butyrate subs...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol lipase-alpha(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50211265(CHEMBL3954476)
Affinity DataIC50:  0.794nMAssay Description:Inhibition of recombinant human DAGLalpha expressed in HEK293T cell membranes overexpressing MAGL using natural substrate 1-stearoyl-2-arachidonoly-s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol lipase-alpha(Mus musculus)
Leiden University

Curated by ChEMBL
LigandPNGBDBM50211265(CHEMBL3954476)
Affinity DataIC50:  3nMAssay Description:Inhibition of mouse DAGL-alpha expressed in HEK293T cell membranes pre-incubated for 20 mins before PNP-butyrate substrate addition and measured afte...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed